Title : AID induces double-strand breaks at immunoglobulin switch regions and c-MYC causing chromosomal translocations in yeast THO mutants.

Pub. Date : 2011 Feb

PMID : 21383964






2 Functional Relationships(s)
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1 AID-induced translocations were strongly enhanced in yeast THO null mutants, consistent with the idea that AID-mediated DSBs depend on R-loop formation. dsbs activation induced cytidine deaminase Homo sapiens
2 AID-induced translocations were strongly enhanced in yeast THO null mutants, consistent with the idea that AID-mediated DSBs depend on R-loop formation. dsbs activation induced cytidine deaminase Homo sapiens