Pub. Date : 2011 Jun
PMID : 21383022
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Protein kinase CbetaII-mediated phosphorylation of endothelial nitric oxide synthase threonine 495 mediates the endothelial dysfunction induced by FK506 (tacrolimus). | Tacrolimus | nitric oxide synthase 3 | Homo sapiens |
| 2 | Protein kinase CbetaII-mediated phosphorylation of endothelial nitric oxide synthase threonine 495 mediates the endothelial dysfunction induced by FK506 (tacrolimus). | Tacrolimus | nitric oxide synthase 3 | Homo sapiens |
| 3 | We have previously shown that FK506 activates Ca(2+)/diacylglycerol-dependent conventional protein kinase C (cPKC), which phosphorylates endothelial nitric oxide synthase (eNOS) at one of its inhibitory sites, Thr495. | Tacrolimus | nitric oxide synthase 3 | Homo sapiens |