Pub. Date : 2011 Feb 16
PMID : 21359217
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Originally, sialoadhesin was characterized as a lymphocyte adhesion molecule, though recently its involvement in internalization of sialic acid carrying pathogens was shown, suggesting that sialoadhesin is an endocytic receptor. | N-Acetylneuraminic Acid | sialic acid binding Ig like lectin 1 | Homo sapiens |
| 2 | Originally, sialoadhesin was characterized as a lymphocyte adhesion molecule, though recently its involvement in internalization of sialic acid carrying pathogens was shown, suggesting that sialoadhesin is an endocytic receptor. | N-Acetylneuraminic Acid | sialic acid binding Ig like lectin 1 | Homo sapiens |
| 3 | Together, these data expand sialoadhesin functionality and show that it can function as an endocytic receptor, a feature that cannot only be misused by sialic acid carrying pathogens, but that may also be used for specific targeting of toxins or antigens to sialoadhesin-expressing macrophages. | N-Acetylneuraminic Acid | sialic acid binding Ig like lectin 1 | Homo sapiens |