| Protein Name | sialic acid binding Ig like lectin 1 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 6614 |
| Gene Symbol | SIGLEC1 |
| UniProt | Q9BZZ2 (SN_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
82
Total Number of Articles : 92 |
Description |
sialic acid binding Ig like lectin 1 |
| Gene Summary |
This gene encodes a member of the immunoglobulin superfamily. The encoded protein is a lectin-like adhesion molecule that binds glycoconjugate ligands on cell surfaces in a sialic acid-dependent manner. It is a type I transmembrane protein expressed only by a subpopulation of macrophages and is involved in mediating cell-cell interactions. The protein plays an important role in multiple human diseases and bacterial and viral infections has been shown to enhance SARS-CoV-2 infection. [provided by RefSeq, Dec 2021] |
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| Properties | |