Title : Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes.

Pub. Date : 2011 Mar 14

PMID : 21357742






1 Functional Relationships(s)
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1 We previously identified Dectin-2 as a receptor for glycans in allergen extracts from the house dust mite Dermatophagoides farinae (Df) that mediates cysteinyl leukotriene (cys-LT) generation from pulmonary CD11c+ cells and from GM-CSF-cultured bone marrow cells (BMCs(GM-CSF)). Polysaccharides integrin subunit alpha X Homo sapiens