Title : [Celecoxib increased cellular ATRA sensitivity of human colon cancer cell lines through COX-2-independent mechanisms].

Pub. Date : 2009 Dec

PMID : 21351468






2 Functional Relationships(s)
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1 Western blotting showed that the expression of RARbeta in HT-29 cell lines increased in celecoxib group and combination group. Celecoxib retinoic acid receptor beta Homo sapiens
2 In conclusion, celecoxib increased expression of RARbeta and cellular ATRA sensitivity through COX-2-independent mechanisms, which may provide a potential strategy for combination therapy. Celecoxib retinoic acid receptor beta Homo sapiens