Title : Inhibition of human melanoma cell growth by the dietary flavonoid fisetin is associated with disruption of Wnt/β-catenin signaling and decreased Mitf levels.

Pub. Date : 2011 Jun

PMID : 21346776






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1 In this study, we show that treatment of 451Lu melanoma cells with the dietary flavonoid fisetin (3,7,3",4"-tetrahydroxyflavone) resulted in decreased cell viability with G1-phase arrest and disruption of Wnt/beta-catenin signaling. flavonoid fisetin catenin beta 1 Homo sapiens