Title : HFE gene variants affect iron in the brain.

Pub. Date : 2011 Apr 1

PMID : 21346098






2 Functional Relationships(s)
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Protein Name
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1 At the cellular level, the HFE mutant protein resulting from the H63D HFE gene variant is associated with iron dyshomeostasis, increased oxidative stress, glutamate release, tau phosphorylation, and alteration in inflammatory response, each of which is under investigation as a contributing factor to neurodegenerative diseases. Glutamic Acid homeostatic iron regulator Homo sapiens
2 At the cellular level, the HFE mutant protein resulting from the H63D HFE gene variant is associated with iron dyshomeostasis, increased oxidative stress, glutamate release, tau phosphorylation, and alteration in inflammatory response, each of which is under investigation as a contributing factor to neurodegenerative diseases. Glutamic Acid homeostatic iron regulator Homo sapiens