Protein Name | homeostatic iron regulator |
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Organism | Homo sapiens |
Gene ID | 3077 |
Gene Symbol | HFE |
UniProt | Q30201 (HFE_HUMAN), F8W7W8 (F8W7W8_HUMAN), B4DV50 (B4DV50_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
167
Total Number of Articles : 984 |
Description |
homeostatic iron regulator |
Gene Summary |
The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. [provided by RefSeq, May 2022] |
synonyms |
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Properties | |