Title : A lead study on oxidative stress-mediated dehydroepiandrosterone formation in serum: the biochemical basis for a diagnosis of Alzheimer's disease.

Pub. Date : 2011

PMID : 21335661






2 Functional Relationships(s)
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1 We previously identified a brain- and cell-specific oxidative stress-mediated mechanism for dehydroepiandrosterone (DHEA) biosynthesis present in rat, bovine, and human brain, independent of the cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17) enzyme activity found in the periphery. Dehydroepiandrosterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 We previously identified a brain- and cell-specific oxidative stress-mediated mechanism for dehydroepiandrosterone (DHEA) biosynthesis present in rat, bovine, and human brain, independent of the cytochrome P450 17alpha-hydroxylase/17,20-lyase (CYP17) enzyme activity found in the periphery. Dehydroepiandrosterone cytochrome P450 family 17 subfamily A member 1 Homo sapiens