Title : Tyrosine kinase blockers: new platelet activation inhibitors.

Pub. Date : 1990 Dec

PMID : 2133252






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Tyrphostins inhibited dose-dependently thrombin-induced aggregation and the release reaction, with a maximum effect at 25 microM. Tyrphostins coagulation factor II, thrombin Homo sapiens
2 Using immunoblots of platelet proteins revealed with an anti-phosphotyrosine antibody, tyrphostins were effective inhibitors of tyrosine phosphorylation elicited by thrombin. Tyrphostins coagulation factor II, thrombin Homo sapiens