Title : Forced Runx1 expression in human neural stem/progenitor cells transplanted to the rat dorsal root ganglion cavity results in extensive axonal growth specifically from spinal cord-derived neurospheres.

Pub. Date : 2011 Nov

PMID : 21322790






1 Functional Relationships(s)
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1 To stimulate axonal growth, we transfected hfNSPC- and hscNSPC-derived neurospheres, prior to their transplantation, with a Tet-Off Runx1-overexpressing plasmid to maintain Runx1 expression in vivo after transplantation. tetramethylenedisulfotetramine RUNX family transcription factor 1 Homo sapiens