Pub. Date : 2011 Apr 25
PMID : 21315711
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Bupivacaine induces apoptosis via mitochondria and p38 MAPK dependent pathways. | Bupivacaine | mitogen-activated protein kinase 14 | Homo sapiens |
| 2 | Bupivacaine-induced reactive oxygen species production results in an alteration in the permeability of the mitochondrial membranes and Cl(-) influx into mitochondria, which seems to be responsible for mitochondrial depolarization and the p38 MAPK activation. | Bupivacaine | mitogen-activated protein kinase 14 | Homo sapiens |