Title : Discovery of a potential allosteric ligand binding site in CDK2.

Pub. Date : 2011 May 20

PMID : 21291269






2 Functional Relationships(s)
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1 In an effort to identify potential target sites for disruption of the CDK-cyclin interaction, we probed the extrinsic fluorophore 8-anilino-1-naphthalene sulfonate (ANS) with human CDK2 and cyclin A using fluorescence spectroscopy and protein crystallography. 8-anilino-1-naphthalenesulfonic acid proliferating cell nuclear antigen Homo sapiens
2 In an effort to identify potential target sites for disruption of the CDK-cyclin interaction, we probed the extrinsic fluorophore 8-anilino-1-naphthalene sulfonate (ANS) with human CDK2 and cyclin A using fluorescence spectroscopy and protein crystallography. 8-anilino-1-naphthalenesulfonic acid proliferating cell nuclear antigen Homo sapiens