Title : Isocitrate dehydrogenase mutations may be a protective mechanism in glioma patients.

Pub. Date : 2011 Apr

PMID : 21284999






1 Functional Relationships(s)
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1 A recent cancer genome-sequencing project revealed that more than 70% of low-grade gliomas bear mutations in one of two NAD(+)-dependent isocitrate dehydrogenase enzymes, namely, IDH1 and IDH2. NAD isocitrate dehydrogenase (NADP(+)) 2 Homo sapiens