Title : Opioid receptor activation: suppression of ischemia/reperfusion-induced production of TNF-α in the retina.

Pub. Date : 2011 Apr

PMID : 21282567






3 Functional Relationships(s)
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1 Ischemia-induced TNF-alpha production was significantly inhibited by morphine. Morphine tumor necrosis factor Rattus norvegicus
2 In astrocytes and microglia, LPS triggered a robust increase in the release of TNF-alpha, which was significantly inhibited (P < 0.05) by morphine. Morphine tumor necrosis factor Rattus norvegicus
3 Naloxone reversed the morphine-induced suppression of TNF-alpha production in vivo and in vitro. Morphine tumor necrosis factor Rattus norvegicus