Title : Specific CLK inhibitors from a novel chemotype for regulation of alternative splicing.

Pub. Date : 2011 Jan 28

PMID : 21276940






1 Functional Relationships(s)
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1 Here, we report the discovery and characterization of the dichloroindolyl enaminonitrile KH-CB19, a potent and highly specific inhibitor of the CDC2-like kinase isoforms 1 and 4 (CLK1/CLK4). KH-CB19 CDC like kinase 1 Homo sapiens