Title : Phytoestrogens directly inhibit TNF-α-induced bone resorption in RAW264.7 cells by suppressing c-fos-induced NFATc1 expression.

Pub. Date : 2011 Feb

PMID : 21268069






2 Functional Relationships(s)
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Protein Name
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1 The phytoestrogens genistein, daidzein, and coumestrol directly suppressed TNF-alpha-induced osteoclastogenesis and bone resorption. Genistein tumor necrosis factor Mus musculus
2 In addition, in the presence of ICI 182,780 genistein and coumestrol (10(-5) -10(-6) M) augmented TNF-alpha-induced osteoclast formation and resorption. Genistein tumor necrosis factor Mus musculus