Pub. Date : 2010 Dec
PMID : 21267696
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nicotine induces upregulated expression of beta defensin-2 via the p38MAPK pathway in the HaCaT human keratinocyte cell line. | Nicotine | defensin beta 4A | Homo sapiens |
| 2 | The purpose of the present study was to investigate the effect of nicotine on the expression pattern of hBD-2 in keratinocytes. | Nicotine | defensin beta 4A | Homo sapiens |
| 3 | qRT-PCR revealed that the expression level of hBD-2 mRNA was significantly higher at 30 and 80 muM nicotine than the control without nicotine (P < 0.05). | Nicotine | defensin beta 4A | Homo sapiens |
| 4 | qRT-PCR revealed that the expression level of hBD-2 mRNA was significantly higher at 30 and 80 muM nicotine than the control without nicotine (P < 0.05). | Nicotine | defensin beta 4A | Homo sapiens |
| 5 | The p38MAP kinase inhibitor abolished the upregulated expression of hBD-2 by nicotine. | Nicotine | defensin beta 4A | Homo sapiens |
| 6 | Both nAChR inhibitors also abolished the upregulation of hBD-2 by nicotine. | Nicotine | defensin beta 4A | Homo sapiens |
| 7 | The present study demonstrated that nicotine causes upregulated expression of hBD-2 via the p38MAP kinase pathway in keratinocytes. | Nicotine | defensin beta 4A | Homo sapiens |