PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
21267696-0	2010	Nicotine induces upregulated expression of beta defensin-2 via the p38MAPK pathway in the HaCaT human keratinocyte cell line.	Nicotine	0-8	defensin beta 4A	Homo sapiens	43-58	
21267696-3	2010	The purpose of the present study was to investigate the effect of nicotine on the expression pattern of hBD-2 in keratinocytes.	Nicotine	66-74	defensin beta 4A	Homo sapiens	104-109	
21267696-7	2010	qRT-PCR revealed that the expression level of hBD-2 mRNA was significantly higher at 30 and 80 muM nicotine than the control without nicotine (P < 0.05).	Nicotine	99-107	defensin beta 4A	Homo sapiens	46-51	
21267696-7	2010	qRT-PCR revealed that the expression level of hBD-2 mRNA was significantly higher at 30 and 80 muM nicotine than the control without nicotine (P < 0.05).	Nicotine	133-141	defensin beta 4A	Homo sapiens	46-51	
21267696-9	2010	The p38MAP kinase inhibitor abolished the upregulated expression of hBD-2 by nicotine.	Nicotine	77-85	defensin beta 4A	Homo sapiens	68-73	
21267696-10	2010	Both nAChR inhibitors also abolished the upregulation of hBD-2 by nicotine.	Nicotine	66-74	defensin beta 4A	Homo sapiens	57-62	
21267696-11	2010	The present study demonstrated that nicotine causes upregulated expression of hBD-2 via the p38MAP kinase pathway in keratinocytes.	Nicotine	36-44	defensin beta 4A	Homo sapiens	78-83