Title : Vulnerability of the cysteine-less proton-coupled folate transporter (PCFT-SLC46A1) to mutational stress associated with the substituted cysteine accessibility method.

Pub. Date : 2011 Apr

PMID : 21256110






2 Functional Relationships(s)
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Protein Name
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1 The current report describes Lys 422 mutations (K422C, K422E) that have no effect on transport activity when introduced into wild-type PCFT but result in a marked loss of activity when introduced into a Cys-less PCFT which is otherwise near-fully functional. Lysine solute carrier family 46 member 1 Homo sapiens
2 The current report describes Lys 422 mutations (K422C, K422E) that have no effect on transport activity when introduced into wild-type PCFT but result in a marked loss of activity when introduced into a Cys-less PCFT which is otherwise near-fully functional. Lysine solute carrier family 46 member 1 Homo sapiens