Title : Tacrolimus modulates liver and pancreas nitric oxide synthetase and heme-oxygenase isoforms and cytokine production after endotoxemia.

Pub. Date : 2011 Mar 15

PMID : 21255669






2 Functional Relationships(s)
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1 Tacrolimus treatment diminished TNF-alpha but not IL-1 expression increase after LPS challenge in hepatic tissue. Tacrolimus tumor necrosis factor Rattus norvegicus
2 Plasmatic NO, CO, TNF-alpha, and IL-1 concentrations increase after LPS challenge was diminished when highest doses of tacrolimus were given. Tacrolimus tumor necrosis factor Rattus norvegicus