Title : Anticoagulant effects of thioanalogs of thrombin-binding DNA-aptamer and their stability in the plasma.

Pub. Date : 2010 Dec

PMID : 21240367






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1 In order to create effective therapeutically significant oligonucleotide structures, a series of analogs of thrombin-binding aptamer d(GGTTGGTGTGGTTGG) containing thiophosphoryl substitutions were synthesized. Oligonucleotides coagulation factor II, thrombin Homo sapiens