Title : Double null cells reveal that CBP and p300 are dispensable for p53 targets p21 and Mdm2 but variably required for target genes of other signaling pathways.

Pub. Date : 2011 Jan 15

PMID : 21220944






1 Functional Relationships(s)
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1 We found that while retinoic acid-inducible gene expression tends to be uniformly dependent on CBP/p300, dsRNA- and serum-inducible genes displayed non-uniform requirements for CBP/p300, with the dsRNA-inducible expression of Ifnb1 (interferon-beta) being particularly dependent on CBP/p300. Tretinoin E1A binding protein p300 Mus musculus