Title : c-Abl regulates Mcl-1 gene expression in chronic lymphocytic leukemia cells.

Pub. Date : 2011 Feb 24

PMID : 21220745






1 Functional Relationships(s)
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1 We show that treatment of CLL cells with Abl-specific siRNA or with imatinib, to inhibit c-Abl activity, results in the down-regulation of Mcl-1 protein and mRNA. Imatinib Mesylate MCL1 apoptosis regulator, BCL2 family member Homo sapiens