Title : Molecular docking and pharmacogenomics of vinca alkaloids and their monomeric precursors, vindoline and catharanthine.

Pub. Date : 2011 Mar 15

PMID : 21219884






1 Functional Relationships(s)
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1 P-glycoprotein-overexpressing multidrug-resistant CEM/VCR1000 cells were highly resistant towards vincristine and cross-resistant to vinblastine, vindesine, and vinorelbine, but not or only weakly cross-resistant to vindoline and catharanthine. Vinblastine ATP binding cassette subfamily B member 1 Homo sapiens