Title : Wld(S), Nmnats and axon degeneration--progress in the past two decades.

Pub. Date : 2010 Mar

PMID : 21203970






2 Functional Relationships(s)
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Protein Name
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1 At molecular level, although Wld(S) is a fusion protein, the nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1) is required and sufficient for the protective effects of Wld(S), indicating a critical role of NAD biosynthesis and perhaps energy metabolism in axon degeneration. NAD nicotinamide nucleotide adenylyltransferase 1 Mus musculus
2 At molecular level, although Wld(S) is a fusion protein, the nicotinamide mononucleotide adenylyl transferase 1 (Nmnat1) is required and sufficient for the protective effects of Wld(S), indicating a critical role of NAD biosynthesis and perhaps energy metabolism in axon degeneration. NAD nicotinamide nucleotide adenylyltransferase 1 Mus musculus