Title : Relationship between CYP1A induction by indole-3-carbinol or flutamide and liver tumor-promoting potential in rats.

Pub. Date : 2011 Sep

PMID : 21203749






1 Functional Relationships(s)
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1 In parallel, I3C, FLU, and BNF markedly increased mRNA levels of Cyp1a1 (50-, 23-, 299-fold) and antioxidant/detoxifying enzymes such as Gpx2 and Nqo1 as shown by real-time reverse transcription-polymerase chain reaction analysis. Flutamide NAD(P)H quinone dehydrogenase 1 Rattus norvegicus