| Protein Name | NAD(P)H quinone dehydrogenase 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 24314 |
| Gene Symbol | Nqo1 |
| UniProt | P05982 (NQO1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
486
Total Number of Articles : 538 |
Description |
NAD(P)H quinone dehydrogenase 1 |
| Gene Summary |
Enables NADH dehydrogenase (quinone) (non-electrogenic) activity and superoxide dismutase activity. Involved in several processes, including regulation of apoptotic process; response to ischemia; and response to tetrachloromethane. Located in dendrite and neuronal cell body. Used to study several diseases, including chronic kidney disease; colon cancer; hypertension; liver cirrhosis; and membranous glomerulonephritis. Biomarker of several diseases, including cerebrovascular disease (multiple); liver disease (multiple); overactive bladder syndrome; status epilepticus; and ureteral obstruction. Human ortholog(s) of this gene implicated in several diseases, including hematologic cancer (multiple); hypertension; lung disease (multiple); macular degeneration; and small cell carcinoma. Orthologous to human NQO1 (NAD(P)H quinone dehydrogenase 1). [provided by Alliance of Genome Resources, Jun 2025] |
| synonyms |
|
| Properties | |