Title : COX-2 inhibition and inhibition of cytosolic phospholipase A2 increase CD36 expression and foam cell formation in THP-1 cells.

Pub. Date : 2011 Feb

PMID : 21181286






1 Functional Relationships(s)
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1 Oil red O staining revealed a profound increase in foam cell transformation of THP-1 macrophages exposed to either celecoxib or AACOCF3 (both 25 muM), supporting a role for the COX pathway in maintaining macrophage cholesterol homeostasis. Celecoxib GLI family zinc finger 2 Homo sapiens