Pub. Date : 2011 Jun
PMID : 21175263
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | But 70Z/Cbl significantly upregulated TAM-induced ERK and AKT activity. | Tamoxifen | mitogen-activated protein kinase 1 | Homo sapiens |
| 2 | CONCLUSIONS: This study demonstrates that c-Src, ERK, and AKT played a protective role during TAM-induced apoptosis, and that c-Cbl sensitized MCF-7 cells to TAM by modulating the expression of c-Src, and TAM-induced ERK and AKT activity. | Tamoxifen | mitogen-activated protein kinase 1 | Homo sapiens |