Title : Natural proteasome inhibitor celastrol suppresses androgen-independent prostate cancer progression by modulating apoptotic proteins and NF-kappaB.

Pub. Date : 2010 Dec 10

PMID : 21170316






1 Functional Relationships(s)
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1 We found that celastrol inhibited cell proliferation in all three AIPC cell lines (PC-3, DU145 and CL1), with IC50 in the range of 1-2 microM. celastrol adhesion G protein-coupled receptor L1 Homo sapiens