Title : NF-κB addiction and its role in cancer: 'one size does not fit all'.

Pub. Date : 2011 Apr 7

PMID : 21170083






2 Functional Relationships(s)
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1 As NF-kappaB is "pre-active" in cancer cells through unrelated mechanisms, classic inhibitors of NF-kappaB (for example, bortezomib) are unlikely to mediate their anticancer effects through suppression of NF-kappaB. Bortezomib nuclear factor kappa B subunit 1 Homo sapiens
2 As NF-kappaB is "pre-active" in cancer cells through unrelated mechanisms, classic inhibitors of NF-kappaB (for example, bortezomib) are unlikely to mediate their anticancer effects through suppression of NF-kappaB. Bortezomib nuclear factor kappa B subunit 1 Homo sapiens