Title : Nature of tyrosinase inactivation in melanosomes.

Pub. Date : 1978 Jul

PMID : 211676






4 Functional Relationships(s)
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1 The decrease in tyrosinase activity following incubation of melanosomes isolated from mouse melanoma with dopa appeared to be related to the degree of in vitro melanization of melanosomes caused by incubation with dopa. Dihydroxyphenylalanine tyrosinase Mus musculus
2 The decrease in tyrosinase activity following incubation of melanosomes isolated from mouse melanoma with dopa appeared to be related to the degree of in vitro melanization of melanosomes caused by incubation with dopa. Dihydroxyphenylalanine tyrosinase Mus musculus
3 The inactivation similarly occurred in the dopa-tyrosinase reaction system containing ascorbic aicd, although in the presence of ascorbic acid the dopa-quinone is immediately converted back to dopa and therefore melanin formation does not take place. Dihydroxyphenylalanine tyrosinase Mus musculus
4 The inactivation similarly occurred in the dopa-tyrosinase reaction system containing ascorbic aicd, although in the presence of ascorbic acid the dopa-quinone is immediately converted back to dopa and therefore melanin formation does not take place. Dihydroxyphenylalanine tyrosinase Mus musculus