Pub. Date : 2010 Dec
PMID : 21159604
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Antagonism of cytotoxic chemotherapy in neuroblastoma cell lines by 13-cis-retinoic acid is mediated by the antiapoptotic Bcl-2 family proteins. | Isotretinoin | BCL2 apoptosis regulator | Homo sapiens |
2 | Thus, combining 13-cis-RA with cytotoxic chemotherapy significantly reduced the cytotoxicity for neuroblastoma in vitro, mediated at least in part via the antiapoptotic Bcl-2 family of proteins. | Isotretinoin | BCL2 apoptosis regulator | Homo sapiens |