Title : Contribution of the C-terminal dipeptide of transforming growth factor-alpha to its activity: biochemical and pharmacologic profiles.

Pub. Date : 1990 Jun 12

PMID : 2115447






1 Functional Relationships(s)
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1 Our data point to the importance of the C-terminal dipeptide, Leu49-Ala50 of TGF-alpha in terms of the binding affinity and intrinsic activity of this polypeptide; and our work provides further evidence for the distinct nature of the EGF-URO/TGF-alpha receptor system present in the CM bioassay preparation. Dipeptides transforming growth factor alpha Homo sapiens