Title : Tumor-specific imaging through progression elevated gene-3 promoter-driven gene expression.

Pub. Date : 2011 Jan

PMID : 21151140






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1 Here we show that the progression elevated gene-3 (PEG-3) promoter, derived from a rodent gene mediating tumor progression and metastatic phenotypes, can be used to drive imaging reporters selectively to enable detection of micrometastatic disease in mouse models of human melanoma and breast cancer using bioluminescence and radionuclide-based molecular imaging techniques. Radioisotopes paternally expressed 3 Mus musculus