Title : FoxO1 mediates an autofeedback loop regulating SIRT1 expression.

Pub. Date : 2011 Feb 18

PMID : 21149440






1 Functional Relationships(s)
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Protein Name
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1 Forkhead transcription factor FoxO1 and the NAD(+)-dependent histone deacetylase SIRT1 are evolutionarily conserved regulators of the development of aging, oxidative stress resistance, insulin resistance, and metabolism in species ranging from invertebrates to mammals. NAD insulin Homo sapiens