Title : Double-stranded RNA induces shedding of the 34-kDa soluble TNFR1 from human airway epithelial cells via TLR3-TRIF-RIP1-dependent signaling: roles for dual oxidase 2- and caspase-dependent pathways.

Pub. Date : 2011 Jan 15

PMID : 21148036






1 Functional Relationships(s)
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1 RNA interference experiments demonstrated that poly (I:C)-induced sTNFR1 shedding is mediated via activation of TLR3-TRIF-RIP1 signaling, with subsequent activation of two downstream pathways. Poly I-C TIR domain containing adaptor molecule 1 Homo sapiens