Title : The reassertion profiles of long acting β2-adrenoceptor agonists in the guinea pig isolated trachea and human recombinant β2-adrenoceptor.

Pub. Date : 2011 Apr

PMID : 21134482






2 Functional Relationships(s)
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1 Long acting beta(2)-adrenoceptor agonists as exemplified by salmeterol and formoterol, exhibit reassertion behaviour in isolated airway preparations. Salmeterol Xinafoate adrenoceptor beta 2 Homo sapiens
2 Results are discussed in the context of the two theories proposed to explain the long duration of action of salmeterol (binding to a specific "exosite" of the beta(2)-adrenoceptor) and formoterol (membrane deposition: micro-kinetic theory). Salmeterol Xinafoate adrenoceptor beta 2 Homo sapiens