Title : Bax regulates production of superoxide in both apoptotic and nonapoptotic neurons: role of caspases.

Pub. Date : 2010 Dec 1

PMID : 21123558






3 Functional Relationships(s)
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1 We used the O(2)( -)-sensitive dye MitoSOX to monitor O(2)( -) in neurons expressing different levels of Bax and mitochondrial superoxide dismutase (SOD2). Superoxides superoxide dismutase 2, mitochondrial Mus musculus
2 We used the O(2)( -)-sensitive dye MitoSOX to monitor O(2)( -) in neurons expressing different levels of Bax and mitochondrial superoxide dismutase (SOD2). Superoxides superoxide dismutase 2, mitochondrial Mus musculus
3 Basal and apoptotic O(2)( -) levels in both SCG and CG neurons were reduced in SOD2 wild-type (WT) cells having lower Bax concentrations. Superoxides superoxide dismutase 2, mitochondrial Mus musculus