Title : Interplay between lysine methylation and Cdk phosphorylation in growth control by the retinoblastoma protein.

Pub. Date : 2011 Jan 19

PMID : 21119616






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In pRb, lysine (K) 810 represents the essential and conserved basic residue (SPXK) required for cyclin/Cdk recognition and phosphorylation. Lysine RB transcriptional corepressor 1 Homo sapiens
2 Thus, the regulation of phosphorylation by Cdks reflects the combined interplay with methylation events, and more generally the targeted methylation of a lysine residue within a Cdk-consensus site in pRb represents an important point of control in cell cycle progression. Lysine RB transcriptional corepressor 1 Homo sapiens