Title : Regulation of human pregnane X receptor and its target gene cytochrome P450 3A4 by Chinese herbal compounds and a molecular docking study.

Pub. Date : 2011 Apr

PMID : 21117944






1 Functional Relationships(s)
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1 Praeruptorin A and C, salvianolic acid B, sodium danshensu, protocatechuic aldehyde, cryptotanshinone, emodin, morin, and tanshinone IIA significantly transactivated the CYP3A4 reporter gene construct in either HepG2 or Huh7 cells. cryptotanshinone cytochrome P450 family 3 subfamily A member 4 Homo sapiens