Title : Insulin-degrading enzyme modulates the natriuretic peptide-mediated signaling response.

Pub. Date : 2011 Feb 11

PMID : 21098034






3 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Three distinct NPs (ANP, BNP, and CNP) can selectively activate natriuretic peptide receptors, NPR-A and NPR-B, raising the cyclic GMP (cGMP) levels. Cyclic GMP natriuretic peptide A Homo sapiens
2 Three distinct NPs (ANP, BNP, and CNP) can selectively activate natriuretic peptide receptors, NPR-A and NPR-B, raising the cyclic GMP (cGMP) levels. Cyclic GMP natriuretic peptide A Homo sapiens
3 IDE rapidly cleaves ANP and CNP, thus inactivating their ability to raise intracellular cGMP. Cyclic GMP natriuretic peptide A Homo sapiens