Protein Name natriuretic peptide A
Organism Homo sapiens
Gene ID 4878
Gene Symbol

NPPA

UniProt P01160 (ANF_HUMAN)
Relationships Total Number of functionally related compound(s) : 655
Total Number of Articles : 1348
Description

natriuretic peptide A

Gene Summary

The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1. [provided by RefSeq, Oct 2015]

synonyms
  • natriuretic peptides A
  • atrial natriuretic factor prohormone
  • atrial natriuretic peptide prohormone
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Properties