Protein Name | natriuretic peptide A |
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Organism | Homo sapiens |
Gene ID | 4878 |
Gene Symbol | NPPA |
UniProt | P01160 (ANF_HUMAN) |
Relationships |
Total Number of functionally related compound(s) :
655
Total Number of Articles : 1348 |
Description |
natriuretic peptide A |
Gene Summary |
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1. [provided by RefSeq, Oct 2015] |
synonyms |
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Properties | |