Title : Mitogenesis induced by pp60v-src is not accompanied by increased expression of immediate early response genes.

Pub. Date : 1990 Feb

PMID : 2108404






1 Functional Relationships(s)
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1 Nonetheless, upon activating the pp60v-src protein kinase there is a marked and rapid increase in the ability of ts LA 29 Rat-1 nuclear extracts to retard the gel migration of oligonucleotides containing the AP-1 binding site, indicating that pp60v-src activity leads to an enhanced functioning of Fos and Jun related proteins that may, in turn, affect their transcriptional activation. Oligonucleotides Fos proto-oncogene, AP-1 transcription factor subunit Rattus norvegicus