Title : Comparative neurochemical profile of 3,4-methylenedioxymethamphetamine and its metabolite alpha-methyldopamine on key targets of MDMA neurotoxicity.

Pub. Date : 2011 Jan

PMID : 21074589






1 Functional Relationships(s)
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1 The aim of the present study was to investigate and compare the effects of MDMA and its metabolite alpha-methyldopamine (MeDA) on several molecular targets, mainly the dopamine and serotonin transporter functionality, to provide evidence for the role of this metabolite in the neurotoxicity of MDMA in rodents. N-Methyl-3,4-methylenedioxyamphetamine solute carrier family 6 member 4 Rattus norvegicus