Title : The calcium-sensing receptor mediates hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells through MEK1/ERK1,2 and PI3K pathways.

Pub. Date : 2011 Mar

PMID : 21073657






1 Functional Relationships(s)
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1 PD98059 (a MEK1 inhibitor) or LY294002 (a PI3K inhibitors) decreased the up-regulation of PCNA expression and the increase of the cell proliferation index induced by hypoxia and GdCl(3) in PASMCs. 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one mitogen activated protein kinase kinase 1 Rattus norvegicus