Pub. Date : 2012 Nov
PMID : 21070506
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | From studies in cultured cells and animal models, nicotine and alcohol are known to regulate extracellular signal-regulated kinase 1 and 2 (ERK1/2). | Nicotine | mitogen-activated protein kinase 3 | Homo sapiens |
2 | Multiple regression analysis revealed a significant relation among the number of cigarettes smoked daily (R(2)=0.266, P=0.003), the Fagerstrom Test for Nicotine Dependence score (R(2)=0.149, P=0.032) and the mRNA expression of ERK1. | Nicotine | mitogen-activated protein kinase 3 | Homo sapiens |