Pub. Date : 2011 Jan
PMID : 21061168
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The first step of iron transport from the blood to the brain is transferrin receptor (TfR)-mediated endocytosis in the capillary endothelial cells. | Iron | transferrin receptor | Rattus norvegicus |
| 2 | The first step of iron transport from the blood to the brain is transferrin receptor (TfR)-mediated endocytosis in the capillary endothelial cells. | Iron | transferrin receptor | Rattus norvegicus |
| 3 | Furthermore, the expression of Tf and TfR in the blood vessels precedes its expression in oligodendrocytes, the main iron-storing cells in the vertebrate brain. | Iron | transferrin receptor | Rattus norvegicus |
| 4 | The specific expression of Tf and TfR in brain perivascular cells and MTP-1 and hephaestin in endothelial cells suggest the possibility that trafficking of elemental iron through perivascular cells may be instrumental in the distribution of iron in the developing central nervous system. | Iron | transferrin receptor | Rattus norvegicus |